Advances in Research of Mechanism of Herb-Drug Interactions

作     者：Mingchen CAO Chuan WANG Zhiwei YANG Zenan ZHANG Wenxiao WANG Hongxia YU Shasha ZHANG Cheng CHENG Wei REN 

作者机构：The Affiliated Hospital of Qingdao UniversityQingdao 266000China 

出 版 物：《Medicinal Plant》 (药用植物：英文版)

年 卷 期：2023年第14卷第1期

页      面：108-113页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主　　题：Herb-drug-interactions Metabolic enzymes Drug transporters CYP450 P-gp 

摘      要：With the concurrent consumption of herbal medicines and conventional drugs,herb-drug interactions(HDIs)have become the most important clinical consequence of this practice.A general overview and the significance of pharmacokinetic and pharmacodynamic HDIs are provided,detailing basic mechanism,especially the metabolic enzymes and drug transporters,such as CYP450 and P-gp.