The sound of movement,a noninvasive surgical procedure for treating Parkinson’s disease
作者机构：Transgenic SectionLaboratory of NeurogeneticsNational Institute on AgingNational Institutes of HealthBethesdaMD 20892U.S.A.
出 版 物：《Aging Communications》 (衰老通讯)
年 卷 期：2023年第5卷第1期
页 面：1-3页
基 金：supported by the Intramural Research Programs of National Institute on Aging NIH(HC ZIA AG000944 AG000928)
主 题：impaired movement treatment
摘 要：Parkinson’s disease(PD)is the second most common degenerative neurological disorder after Alzheimer’s *** one of fastest growing neurological conditions,PD affects millions of elderly people *** patients display progressive motor symptoms,including resting tremor,slowed movement,impaired posture and balance,and rigid muscles[1].Additionally,they also often suffer from chronic pain,depression,dementia,and other non-motor symptoms[2].Medications and surgery can improve patient’s motor performance to some degree,while the treatment for non-motor conditions is ***,long-term medication can cause severe side effects,such as dyskinesia and impulse control disorders[3,4].Therefore,new mechanistic insights and therapeutic agents/procedures are still needed to improve the treatment of increasing number of PD patients.
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