Transplantation of primary and reversibly immortalized human liver cells and other gene therapies in acute liver failure and decompensated chronic liver disease

作     者：Stephen M.Riordan Roger Williams 

作者机构：Institute of HepatologyUniversity College London and University College London HospitalsLondonEngland Department of GastroenterologyThe Prince of Wales HospitalSydneyAustralia Institute of HepatologyUniversity College London and University College London HospitalsLondonEngland 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2000年第6卷第5期

页      面：636-642页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：liver failure acute liver diseases liver transplantation gene therapy animals laboratory transfering growth factor beta 

摘      要：Studies performed in experimental small animalswith hepatic-based metabolic disorders but nostructural liver disease,including Gunn andanalbuminaemic rats and rabbits with inherited low-density lipoprotein receptor deficiency,have shownthat up to 95% of hepatocytes transplanted into thespleen or liver remain in these sites,withimprovement in metabolic function