An Efficient and Green Procedure for the Knoevenagel Condensation Catalyzed by Urea

作     者：孙崎 史兰香 葛泽梅 程铁明 李润涛 

作者机构：SchoolofPharmaceuticalSciencesPekingUniversityBeijing100083China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2005年第23卷第6期

页      面：745-748页

核心收录：

学科分类：081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 0822[工学-轻工技术与工程] 

主　　题：Knoevenagel condensation green procedure urea catalyst active methylene 

摘      要：An efficient and green procedure for the urea catalyzed Knoevenagel condensation was developed. In the presence of a catalytic ammount of urea, stoichiometric aldehyde and active methylene compound reacted under solvent-free conditions at 100 °C for 5-60 min to give nearly quantitative yield of product.