Epidemiologic differences in esophageal cancer between Asian and Western populations

作     者：Han-Ze Zhang Guang-Fu Jin Hong-Bing Shen 

作者机构：Affiliation:Department of Epidemiology and BiostatisticsSchoolof Public HealthNanjing Medical UniversityNanjingJiangsu 210029P.R.China 

出 版 物：《Chinese Journal of Cancer》 (Chinese Journal of Cancer)

年 卷 期：2012年第31卷第6期

页      面：281-286页

核心收录：

学科分类：090603[农学-临床兽医学] 1002[医学-临床医学] 09[农学] 0906[农学-兽医学] 

主　　题：食管癌 亚洲人 流行病学 西方 鳞状细胞癌 人群 危险因素 全球范围 

摘      要：Esophageal cancer is a common cancer worldwide and has a poor prognosis. The incidence of esophageal squamous cell cancer has been decreasing, whereas the incidence of esophageal adenocarcinoma has been increasing rapidly, particularly in Western men. Squamous cell cancer continues to be the major type of esophageal cancer in Asia, and the main risk factors include tobacco smoking, alcohol consumption, hot beverage drinking, and poor nutrition. In contrast, esophageal adenocarcinoma predominately affects the whites, and the risk factors include smoking, obesity, and gastroesophageal reflux disease. In addition, Asians and Caucasians may have different susceptibilities to esophageal cancer due to different heritage backgrounds. However, comparison studies between these two populations are limited and need to be addressed in the near future. Ethnic differences should be taken into account in preventive and clinical practices.