Metabolic-associated fatty liver disease:New nomenclature and approach with hot debate

作     者：Yasser Fouad 

作者机构：Department of Gastroenterology and Endemic MedicineMinia UniversityMinia 19111Egypt 

出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)

年 卷 期：2023年第15卷第2期

页      面：123-128页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Non-alcoholic fatty liver disease Metabolic-associated fatty liver disease Liver disease Fibrosis New nomenclature Redefinition 

摘      要：An international panel recently proposed an update to the terminology and diagnostic criteria for fatty liver *** experts proposed a change in the nomenclature from non-alcoholic fatty liver disease(NAFLD)to metabolic(dysfunction)-associated fatty liver disease(MAFLD).This single-letter change,we believe,heralds the dawn of a new era in clinical practice and in clinical and basic research as *** new nomenclature with the easily applicable approach has stimulated the enthusiasm of the researchers worldwide,resulting in a large number of publications over the past two *** recent studies have provided tremendous evidence of the superiority of the MAFLD criteria over the NAFLD *** studies in different geographic areas of the world including the United States,Europe,and Asia on a large number of patients proved that the utility of MAFLD criteria was higher than that of the NAFLD criteria in different aspects of fatty liver ***,many societies,physician and nurse groups,health stakeholders,representatives of regulatory sciences,and others endorsed the new *** we highlight the endorsement of the new name by different societies and groups and the outcome of different studies on the new nomenclature in addition to a short discussion of the debate by some experts.