Functional constipation in children:What physicians should know
作者机构：Thailand and Department of PediatricsFaculty of MedicineChulalongkorn UniversityBangkok 10330BangkokThailand Faculty of MedicineCan Tho University of Medicine and PharmacyCan Tho City 9000Viet Nam Thai Pediatric GastroenterologyHepatology and Immunology Research UnitDivision of GastroenterologyDepartment of PediatricsKing Chulalongkorn Memorial Hospital and Thai Red CrossFaculty of MedicineChulalongkorn UniversityBangkok 10330Thailand
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2023年第29卷第8期
页 面：1261-1288页
核心收录：
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
基 金：Thailand and Thailand Science Research and Innovation Fund Chulalongkorn University No.HEA663000047
主 题：Constipation Children Laxative Treatment Toilet training Herbal
摘 要：Functional constipation(FC)is considered the most common functional gastrointestinal disorder in children with a pooled global prevalence of 14.4%(95%confidence interval:11.2-17.6)when diagnosed based on the Rome IV *** pathophysiological mechanisms are thought be multifactorial and complicated,resulting in difficult ***,the most effective medication,when used in parallel with toilet training,is osmotic ***’s adherence to medication and parental concern regarding long-term laxative use are the main contributors to treatment ***,novel therapies with a high safety profile have been developed,such as probiotics,synbiotics,serotonin 5-hydroxytryptamine 4 receptor agonists,chloride channel activators,and herbal and transitional medicines;nonetheless,well-designed research to support the use of these therapies is *** review aims to focus on multiple aspects of FC in children,including global prevalence,pathogenesis,diagnostic criteria,tools,as well as conventional and novel treatment options,such as non-pharmacological management,including adequate fiber and fluid intake,physiotherapy,or *** also report that in very difficult cases,surgical intervention may be required.
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