Effects of dissolved oxygen on intestinal bacterial community and immunity of Atlantic salmon Salmo salar

作     者：Shihong XU Yanfeng WANG Caixia GAO Sarath BABU V Jun LI Qinghua LIU Zhizhong XIAO Yingxuan XU Chunyan ZHAO Li LIN Liang CHI Shihong XU;Yanfeng WANG;Caixia GAO;Sarath BABU V;Jun LI;Qinghua LIU;Zhizhong XIAO;Yingxuan XU;Chunyan ZHAO;Li LIN;Liang CHI

作者机构：Department of Aquatic Animal MedicineCollege of FisheriesHuazhong Agricultural UniversityWuhan 430070China College of Veterinary MedicineQingdao Agricultural UniversityQingdao 266109China Laboratory Animal and Comparative Medicine TeamState Key Laboratory of Veterinary BiotechnologyHarbin Veterinary Research InstituteChinese Academy of Agricultural Sciences(CAAS)Harbin 150069China CAS Key Laboratory of Experimental Marine BiologyInstitute of OceanologyChinese Academy of SciencesQingdao 266071China Guangdong Provincial Water Environment and Aquatic Products Security Engineering Technology Research CenterGuangzhou Key Laboratory of Aquatic Animal Diseases and Waterfowl BreedingZhongkai University of Agriculture and EngineeringGuangzhou 510225China University College LondonLondon WC1E 6BTUnited Kingdom School of Marine Science and EngineeringQingdao Agricultural UniversityQingdao 266109China 

出 版 物：《Journal of Oceanology and Limnology》 (海洋湖沼学报（英文）)

年 卷 期：2023年第41卷第1期

页      面：364-375页

核心收录：

学科分类：0710[理学-生物学] 090801[农学-水产养殖] 0908[农学-水产] 0707[理学-海洋科学] 09[农学] 

基　　金：Supported by the Shandong Province Key Research and Invention Program(No.2017CXGC010K) the China Agriculture Research System(No.CARS-47) the National Key Research and Development Program(No.2018YFD0901204) the National Infrastructure of Fishery Germplasm Resource(No.2019DKA30470) the Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology(Qingdao)(No.2018SDKJ0502-2) the National Natural Science Foundation of China(Nos.31872606,31572657,U1701233,31402283,31802319) the Department of Agriculture and Rural Areas of Guangdong Province(No.KA1911101) the Natural Science Foundation of Shandong Province(No.ZR2018BC053) the Agricultural Application Technology Innovation Project of Shandong Province in 2018/2019(No.SD2019YY011) the Shandong Province Major Scientific and Technological Innovation Projects(No.2019JZZY020710) 

主　　题：Atlantic salmon dissolved oxygen(DO) immune responses microbiota intestine 

摘      要：Dissolved oxygen(DO)is one of most important factors which affect wide range physiologic features of including immune responses and intestinal bacterial ***,the underlying mechanisms remain *** address this question,the intestinal bacterial community compositions and the immune features of Atlantic salmon(Salmo salar)grown in recirculating aquaculture systems(RAS)were *** were reared under different DO saturation levels,e.g.,200% saturation named high group(H),100%saturation named control group(CK),and 60%saturation named lower group(L).Large variations in the operational taxonomic units(OTUs)frequency distribution for the intestinal bacterial community of Atlantic salmon were *** intestinal bacterial community of all groups was dominated mainly by three phyla,e.g.,***,and ***,Acinetobacter baumannii,an opportunistic pathogen of salmon was increased significantly in L *** further monitored the immunity features of fish under different DO *** results show that leucocyte number,cortisol level,the expressions of interleukin-1β(IL-1β),Toll-like receptor 4(TLR4),and nucleotide-binding oligomerization domain like protein 2(NOD2)were higher at significant levels in the L group than those in the other two ***4 and NOD2 are usually related with the bacterial infections;therefore,it is reasonable to believe that the stronger immune responses observed in the L group might be related with the higher abundance of *** in the inte stine of Atlantic ***,these findings demonstrated that low DO level may induce stronger immunity responses in Atlantic salmon.