Trajectory and predictors of cartilage damage in three compartments of the knees at risk for osteoarthritis

作     者：Limin Wu Yuan Liu Haibo Si Mingyang Li Yi Zeng Yuangang Wu Bin Shen Limin Wu;Yuan Liu;Haibo Si;Mingyang Li;Yi Zeng;Yuangang Wu;Bin Shen

作者机构：Department of OrthopaedicsOrthopedic Research InstituteWest China HospitalSichuan UniversityChengduSichuan 610041China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2022年第135卷第23期

页      面：2896-2898页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：the National Natural Science Foundation of China(No.81974347) National Clinical Research Center for Geriatrics,West China Hospital,Sichuan University(No.Z20191008) Science and Technology Foundation of Sichuan Province of China(No.2021YFH0094) 

主　　题：damage knee cartilage 

摘      要：To the Editor:Osteoarthritis(OA)is a prominent disabling disease characterized by progressive articular cartilage damage coupled with deterioration in the subchondral bone and other structures of the joint,and is ranked as the 12th highest disease contributing to global disability.[1]The course of knee OA is considerably long and can affect three knee compartments(the patellofemoral joint[PFJ],medial tibiofemoral joint[MTFJ],and lateral tibiofemoral joint[LTFJ])alone or in combination,resulting in a large variation in the occurrence of cartilage damage in the three compartments.[2]We aimed to determine the baseline predictors associated with distinct tricompartmental trajectories of cartilage damage in knees at risk for OA.