Bacteriophages as antimicrobial agents against major pathogens in swine： a review

作     者：Jiancheng Zhang Zhen Li Zhenhui Cao Lili Wang Xiaoyu Li Shuying Li Yongping Xu 

作者机构：School of Life Science and BiotechnologyDalian University of TechnologyDalian 116024China Ministry of Education Center for Food Safety of Animal OriginDalian 116600China Faculty of Animal Science and TechnologyYunnan Agricultural UniversityKunming 650201China Dalian SEM Bio-Engineering Technology Co.Ltd.Dalian 116620China 

出 版 物：《Journal of Animal Science and Biotechnology》 (畜牧与生物技术杂志（英文版）)

年 卷 期：2016年第7卷第1期

页      面：50-56页

核心收录：

学科分类：090603[农学-临床兽医学] 09[农学] 0906[农学-兽医学] 

基　　金：the National Public Science and Technology Research Funds Projects of Ocean(Grant No.201405003-3) 

主　　题：Antibiotic resistance Bacteriophage Food safety Phage therapy Swine 

摘      要：In recent years, the development of antibiotic resistant bacteria has become a global concern which has prompted research into the development of alternative disease control strategies for the swine industry. Bacteriophages （viruses that infect bacteria） offer the prospect of a sustainable alternative approach against bacterial pathogens with the flexibility of being applied therapeutically or for biological control purposes. This paper reviews the use of phages as an antimicrobial strategy for controlling critical pathogens including Salmonella and Eschefich[a coli with an emphasis on the application of phages for improving performance and nutrient digestibility in swine operations as well as in controlling zoonotic human diseases by reducing the bacterial load spread from pork products to humans through the meat,