Effect of mucin production on survival in colorectal cancer:A case-control study

作     者：Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine 

作者机构：Division of Hematology-Oncology Internal Medicine American University of Beirut Division of Gastroenterology Internal Medicine American University of Beirut Department of Pathology American University of Beirut 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2008年第14卷第45期

页      面：6981-6985页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：结肠癌 直肠癌 癌细胞 治疗 临床 

摘      要：AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor ***: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls ( 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed.