Application of optogenetics in the study of gastrointestinal motility:A mini review

作     者：Song Zhao Ting Zhang Weidong Tong 

作者机构：Department of General SurgeryGastric and Colorectal Surgery DivisionArmy Medical Center(Daping Hospital)Army Medical University ChongqingP.R.China Department of General Surgery The 983th Hospital of Joint Logistic Support Force of People's Liberation Army TianjinP.R.China 

出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)

年 卷 期：2023年第16卷第3期

页      面：78-84页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：This work was funded by the National Natural Science Foundation of China to WT 

主　　题：Gastrointestinal motility optogenetics 

摘      要：Disorders of gastrointestinal(GI)motility are associated with various symptoms such as nausea,vomiting,and ***,the underlying causes of impaired GI motility remainunclear,which has led to variation in the efficacy of therapies to treat GI ***-netics is a novel approach through which target cells can be precisely controlled by light and hasshown great potential in GI motility ***,we summarized recent studies of GI motilitypatterns utilizing optogenetic devices and focused on the ability of opsins,which are geneticallyexpressed in different types of cells in the gut,to regulate the excitability of target *** hopethat our review of recent findings regarding optogenetic control of GI cells broadens the scope ofapplication for optogenetics in GI motility studies.