Cell-scaffold interactions in tissue engineering for oral and craniofacial reconstruction

作     者：Fushi Wang Xinjie Cai Ya Shen Liuyan Meng 

作者机构：The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)and Key Laboratory of Oral Biomedicine Ministry of EducationSchool and Hospital of StomatologyWuhan UniversityWuhanChina Department of Cariology and EndodonticsHospital of StomatologyWuhan UniversityWuhanChina Department of ProsthodonticsHospital of StomatologyWuhan UniversityWuhanChina Division of EndodonticsDepartment of Oral Biological and Medical SciencesFaculty of DentistryUniversity of British ColumbiaVancouverCanada 

出 版 物：《Bioactive Materials》 (生物活性材料（英文）)

年 卷 期：2023年第23卷第5期

页      面：16-44页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：The article was supported by the National Natural Science Foundation of China(No.81870761,82071107) the Fundamental Research Funds for the Central Universities(No.2042020kf0189) 

主　　题：Scaffolds Tissue engineering Interactions Cells 

摘      要：Tissue engineering(TE)is critical in oral and craniofacial *** of the most popular topics on the biomaterial-based tissue regeneration process may be the interaction between cells and *** increasing number of studies have identified the variables affecting cell-scaffold *** creation and investigation of new scaffolds for TE and regenerative medicine based on specific interactions have become possible owing to these *** review discusses the effects of various types of scaffold materials on cells in *** the intrinsic properties of scaffolds are essential,the influence of the physical,chemical,mechanical,and biological characteristics of scaffold materials on cell-scaffold interaction that has been discovered in recent research is elaborated in this *** components carried by scaffolds,the degradation process,and the role of degraded products in cell-scaffold interactions are ***,the roles of cells,including cell types,functions,and adhesion mechanisms,and extracellular matrix are ***,the latest research progress on cell-scaffold interactions among various engineered tissues or organs in the oral and craniofacial region is summarized.A deeper understanding of cell-scaffold interactions is anticipated to benefit the development of TE and regenerative medicine.