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A Simple Over-Oxidized Molecularly Imprinted Polypyrrole for the Sensitive Detection of Dopamine in Human Serum

A Simple Over-Oxidized Molecularly Imprinted Polypyrrole for the Sensitive Detection of Dopamine in Human Serum

作     者:Sarra Slimi Chama Mabrouk Houcine Barhoumi Nicole Jaffrezic-Renault Sarra Slimi;Chama Mabrouk;Houcine Barhoumi;Nicole Jaffrezic-Renault

作者机构:Laboratory of Advanced Materials and Interfaces Faculty of Sciences University of Monastir Monastir Tunisia Institute of Analytical Sciences University of Lyon Villeurbanne France 

出 版 物:《Journal of Sensor Technology》 (传感技术(英文))

年 卷 期:2022年第12卷第3期

页      面:33-44页

学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程(可授工学、理学学位)] 0703[理学-化学] 

主  题:Dopamine Molecularly Imprinted Polymers Over-Oxidized Polypyrrole Square Wave Voltammetry 

摘      要:A simple electrochemical sensor for dopamine detection, is based on molecularly imprinted and electropolymerized over-oxidized polypyrrole (OPPy). The MIP-based electrode is obtained by electrocopolymerization of pyrrole (0.1 M) in the presence of the template molecular (dopamine, DA) (10-3 M). The square wave voltammetry (SWV) is used for the detection of dopamine in buffer solution. The current peak obtained at the MIP electrode was proportional to the logarithm of the DA concentration in the range of 10-11 to 5 × 10-8 M with a detection limit of 10-11 M. The proposed sensor was used for the detection of DA in spiked blood serum, satisfactory results were obtained.

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