Mushroomβ-glucan and polyphenol formulations as natural immunity boosters and balancers:nature of the application

作     者：Maja Kozarski Anita Klaus Leo van Griensven Dragica Jakovljevic Nina Todorovic Wan Abd Al Qadr Imad Wan-Mohtar Jovana Vunduk Maja Kozarski;Anita Klaus;Leo van Griensven;Dragica Jakovljevic;Nina Todorovic;Wan Abd Al Qadr Imad Wan-Mohtar;Jovana Vunduk

作者机构：Institute of Food Technology and BiochemistryFaculty of AgricultureUniversity of BelgradeBelgrade 11080Serbia Plant Research InternationalWageningen University and Research CentreWageningen 6700 AAThe Netherlands Institute of ChemistryTechnology and MetallurgyUniversity of BelgradeBelgrade 11000Serbia Functional Omics and Bioprocess Development LaboratoryInstitute of Biological SciencesFaculty of ScienceUniversiti MalayaKuala Lumpur 50603Malaysia Institute of General and Physical ChemistryUniversity of BelgradeBelgrade 11158Serbia 

出 版 物：《Food Science and Human Wellness》 (食品科学与人类健康（英文）)

年 卷 期：2023年第12卷第2期

页      面：378-396页

核心收录：

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 083201[工学-食品科学] 

基　　金：supported by the Science Fund of the Republic of Serbia #Grant No:7748088。 

主　　题：Mushrooms β-Glucan Polyphenols Immunity boosters Superfood Natural cosmetics 

摘      要：Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet.These valuable organisms are more than food,they fit in perfectly as a novel market group known as nutra-mycoceuticals.Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry.Wellness and cosmetic companies are increasingly using mushroom extracts rich in these ingredients.This review considers the basic molecular immunomodulatory mechanisms of action of the most commonly used mushroom dietary fibers,β-glucans.The literature data on their bioavailability,metabolic transformations,preclinical and human clinical research,and safety are discussed.Immunomodulatory mechanisms of polyphenol ingredients are also considered.These molecules present great potential in the design of the new immunity balancer formulations according to their widespread structural diversity.Finally,we draw attention to the perspectives of modern trends in mushroom nutraceutical and cosmeceutical formulations to strengthen and balance immunity.