New insights to occult gastrointestinal bleeding: From pathophysiology to therapeutics
New insights to occult gastrointestinal bleeding: From pathophysiology to therapeutics作者机构：Department of Gastroenterology University Hospital Virgende Las Nieves 18014 Granada Spain Department of Gastroenterology University Hospital Virgen deLas Nieves 18014 Granada Spain Endoscopy Unit Department of Gastroenterology University Hospital Virgen de Las Nieves 18014 Granada Spain
出 版 物：《World Journal of Gastrointestinal Pathophysiology》 (世界胃肠病理生理学杂志（英文版）（电子版）)
年 卷 期：2014年第5卷第3期
页 面：271-283页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Obscure gastrointestinal bleeding Angiodysplasia Wireless capsule endoscopy Double balloon enteroscopy
摘 要：Obscure gastrointestinal bleeding is still a clinical challenge for gastroenterologists. The recent development of novel technologies for the diagnosis and treatment of different bleeding causes has allowed a better management of patients, but it also determines the need of a deeper comprehension of pathophysiology and the analysis of local expertise in order to develop a rational management algorithm. Obscure gastrointestinal bleeding can be divided in occult, when a positive occult blood fecal test is the main manifestation, and overt, when external sings of bleeding are visible. In this paper we are going to focus on overt gastrointestinal bleeding, describing the physiopathology of the most usual causes, analyzing the diagnostic procedures available, from the most classical to the novel ones, and establishing a standard algorithm which can be adapted depending on the local expertise or availability. Finally, we will review the main therapeutic options for this complex and not so uncommon clinical problem.
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