Copper-Mediated and Catalyzed C-H Bond Amination via Chelation Assistance: Scope, Mechanism and Synthetic Applications
作者机构：College of ChemistryGuangdong University of Petrochemical TechnologyMaomingGuangdong 525000China Fine Chemical Industry Research InstituteSchool of ChemistrySun Yat-sen UniversityGuangzhouGuangdong 510275China
出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)
年 卷 期：2022年第40卷第10期
页 面：1204-1223页
核心收录：
学科分类：07[理学] 070304[理学-物理化学(含∶化学物理)] 0703[理学-化学]
基 金：We are grateful for financial support from the National Natural Science Foundation of China(Nos.21938001,21961160741,22078072) the Special Innovation Project of Guangdong Provincial Department of Education(No.2021KTSCX082) the Science and Technology Plan Project of Maoming City(Nos.2020581,2021009,2021012) the Guangdong Basic and Applied Basic Research Foundation(No.2019A1515110346) the Scientific Research Foundation of Guangdong University of Petrochemical Technology(Nos.517152,2019rc053).
主 题：Copper Chelation assistance CH amination N-Heterocycle synthesis Cross-coupling
摘 要：Nitrogen-containing compounds are ubiquitously found in the fields of organic chemistry,pharmaceuticals,agrochemicals,medicinal chemistry and functional materials.The C-H bond amination reaction is one of the most straightforward protocols in the CN bond formation,showingstepandatomiceconomy.As a catalyst for C-H amination reaction,copper exhibits its unique catalytic properties due to easily accessible oxidation states.The research progress of copper-catalyzed C-H amination in recent years is summarized.At the same time,reaction mechanisms are also briefly described in representative aminations to provide insights for the development prospects of highly practical and more environmentally benignprocesses.
维普期刊数据库