Lymph node metastasis from non-melanoma skin cancer

作     者：Robbie S.R.Woods Jack F.C.Woods Conall W.R.Fitzgerald Ehab Alameer Joseph Lopez Bhuvanesh Singh Jatin P.Shah Robbie S.R.Woods;Jack F.C.Woods;Conall W.R.Fitzgerald;Ehab Alameer;Joseph Lopez;Bhuvanesh Singh;Jatin P.Shah

作者机构：Department of Head&Neck SurgeryMemorial Sloan Kettering Cancer CenterNew YorkNY 10065USA Plastic&Reconstructive SurgeryMemorial Sloan Kettering Cancer CenterNew YorkNY 10065USA 

出 版 物：《Journal of Cancer Metastasis and Treatment》 (癌症转移与治疗（英文版）)

年 卷 期：2022年第8卷第1期

页      面：379-392页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Neck non-melanoma cutaneous malignancy skin neoplasms lymph nodes lymphatic metastasis 

摘      要：The management of non-melanoma skin cancers metastatic to the neck is challenging due to variability in biological behavior and patterns of regional lymphatic *** non-melanoma skin cancers to the parotid and neck often behave aggressively,with a high incidence of local recurrence after treatment and reduced five-year survival *** of lymphatic spread are different from those seen in mucosal squamous cell carcinoma,with higher prevalence of disease in the parotid and superficial *** factors require that treatment is individualized to achieve optimal ***,the management of non-melanoma skin cancers metastatic to lymph nodes has involved surgical excision followed by adjuvant radiation ***,novel systemic therapies are showing promising results and their role in the management of these cancers is evolving.