Batch Preparation and Characterization of Electrospun Porous Polylactic Acid‑Based Nanofiber Membranes for Antibacterial Wound Dressing

作     者：Jing Yin Lan Xu Adnan Ahmed 

作者机构：National Engineering Laboratory for Modern SilkCollege of Textile and Clothing EngineeringSoochow UniversitySuzhouChina 

出 版 物：《Advanced Fiber Materials》 (先进纤维材料（英文）)

年 卷 期：2022年第4卷第4期

页      面：832-844页

核心收录：

学科分类：0821[工学-纺织科学与工程] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：The work is supported financially by National Natural Science Foundation of China(Grant no.11672198) Jiangsu Higher Education Institutions of China(Grant no.20KJA130001) Six Talent Peaks Project of Jiangsu Province(Grant no.GDZB-050) PAPD(A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions) 

主　　题：Batch preparation Polylactic acid/chitosan/aloin Nanofiber membranes Spherical section free surface electrospinning Antibacterial wound dressings 

摘      要：A good wound dressing needs to promote wound healing and tissue repair when the skin is *** this study,a self-made spherical section free surface electrospinning device was used to produce large quantities of electrospun porous polylactic acid(PLA)/chitosan(CS)/aloin nanofiber membranes(NFMs)for antibacterial wound *** porous structures of PLAbased nanofibers were controlled by adjusting the weight ratios of mixed solvent and *** results showed that highquality porous PLA/CS/aloin(PCA)NFMs were obtained when the weight ratios of chloroform/N,N-dimethylformamide and PLA:CS were 90/10 and 7:1,*** porous PCA NFMs exhibited high porosity,acceptable mechanical properties,moderate hydrophobicity,good swelling property,and high water vapor transmission ***,they also showed excellent blood coagulative,antibacterial,biocompatible properties,which had the potential to be used in the application of antibacterial wound dressings.