Copper-Catalyzed [3 + 2 + 1] Cycloaddition of Alkenes with Benzoquinones and Dicarbonyl Compounds via Tandem Oxidative Dicarbofunctionalization/Cyclization Sequence

作     者：Tianxing Du Song Li Yunfei He Huan Long Xigong Liu Hai-Bei Li Lei Liu Tianxing Du;Song Li;Yunfei He;Huan Long;Xigong Liu;Hai-Bei Li;Lei Liu

作者机构：School of Chemistry and Chemical EngineeringShandong University JinanShandong 250100China School of OceanShandong UniversityWeihaiShandong 264209China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2022年第40卷第14期

页      面：1681-1686,I0002页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the funding support of the National Natural Science Foundation of China(Nos.92156008,22161142016,21971148) the China Postdoctoral Science Foundation(No.2019M662321) the Postdoctoral Innovation Project of Shandong Province(No.202001003) 

主　　题：Alkene dicarbofunctionalization Cyclization Three-component C-H Activation Oxidation 

摘      要：Developed is an efficient three-component [3 + 2 + 1] cycloaddition of simple alkenes with two C—H substrates via oxidative dicarbofunctionalization/cyclization sequence. The copper-catalyzed reaction involves the formation of two C—C bonds and one C—O bond through the cleavage of three C—H bonds in a single operation. The method has an excellent functional group tolerance, and features a broad substrate scope, affording a variety of functionalized chromenes in good yields.