Th17 Cells and Tregs in HTLV-1 Infection

作     者：Nafiseh Saghafi Elham Abdollahi Malihe Hasanzadeh Mofrad 

作者机构：Department of Gynecology and ObstetricsMashhad University of Medical SciencesMashhadIran Immunology Research Center Inflammation and Inflammatory Disease Research CentreMashhad University of Medical SciencesMashhadIran 

出 版 物：《Journal of Clinical and Nursing Research》 (临床护理研究（英文）)

年 卷 期：2022年第6卷第3期

页      面：122-127页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Tregs Th17 cells HTLV-1,HAMP/TSP 

摘      要：HTLV-1(human T-lymphotropic virus type 1)causes chronic infection ofhuman T ***-1 infection is known to be related to multiple diseases,including neoplastic growth of HTLV-1-infected T cells(ATL)and neoplastic inflammatory conditions,such as HTLV-1-associated myelopathy/tropical spastic paraparesis(HAM/TSP),Sjogren s syndrome with arthritis,polymyositis uveitis,and *** T cells(Tregs)regulate inflammatory cells,such as Th17 *** purpose of this study was to evaluate Tregs and Th17 cells,as well as the expression of related transcription factors(ROR-γ1 and FOXP3)and cytokines(IL-10,TGF-β,IL-6,and IL-17A)in HTLV-1 infection.