Objective and subjective scar aesthetics with topical Manuka honey post-thyroidectomy:A randomized control study

作     者：Andrew Thamboo Graeme Mulholland Kathleen Matthews Noel Ayoub Donald Anderson Thamboo Andrew;Mulholland Graeme;Matthews Kathleen;Ayoub Noel;Anderson Donald

作者机构：Department of 0tolaryngology e Head and Neck Surgery Stanford University School of Medicine 801 Welch Road Stanford CA 94305 USA 

出 版 物：《World Journal of Otorhinolaryngology-Head and Neck Surgery》 (世界耳鼻咽喉头颈外科杂志（英文）)

年 卷 期：2016年第2卷第4期

页      面：-页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Aesthetics Honey Naturopathic Scar Thyroid Thyroidectomy Topical Wound healing 

摘      要：UNASSIGNED:Honey (Manuka honey) has proven to be effective in improving acute and chronic wound healing presumably due to its antibacterial and anti-inflammatory properties. The aim is to determine if Manuka honey decreases scar formation and results in a cosmetically appealing scar.;UNASSIGNED:A prospective single-blinded randomized control trial was performed. All patients received an 8 cm incision. Patients randomized to honey treatment were instructed to apply Manuka honey paste topically to the incision site once per day post surgery for 4 weeks. The patients scar was then analyzed objectively by a blinded observer and subjectively at 4 and 8 weeks postoperatively. The primary outcome measure used was the Patient and Observer Scar Assessment Scale (POSAS).;UNASSIGNED:A total of 21 patients completed the entire scar analysis (honey treatment = 9, standard treatment = 12). There was no statistically significant difference between patient scar assessment scale and observer scar assessment scale at 4 and 8 weeks postoperatively.;UNASSIGNED:Despite Honey s reported anti-inflammatory and antibacterial properties, this study did not show a difference in scar appearance when applied.