Modeling of ultrasound contrast agents bubble dynamics with modified surface tension coefficient

作     者：ZHENG LuJie TU Juan CHEN WeiZhong 

作者机构：Key Laboratory of Modern Acoustics and Institute of Acoustics Nanjing University Nanjing 210093 China 

出 版 物：《Chinese Science Bulletin》 (CHINESE SCIENCE BULLETIN)

年 卷 期：2009年第54卷第19期

页      面：3501-3507页

核心收录：

学科分类：0810[工学-信息与通信工程] 08[工学] 081002[工学-信号与信息处理] 

基　　金：Supported by the National Natural Science Foundation of China (Grant Nos. 10434070, 10704037) Young Scholar Technological Innovation Projects of Jiangsu Province (China) (Grant No. BK2007569) Research Fund for Doctoral Program (for new scholars) of Higher Education of China (Grant No. 20070284070) Ministry of Education Priorities Project (Grant No. 103078) 

主　　题：超频率音响 光散射 STD 建模 

摘      要：The current work proposes a model describing the dynamics of coated microbubbles, which simplifies the traditional three-layer model to a two-layer one by introducing a visco-elastic interface with variable surface tension coefficients to connect the gas zone and the liquid zone. In the modified model, the traditional two interfaces boundary conditions are combined into one to simplify the description of the bubble. Moreover, the surface tension coefficient is defined as a function of bubble radius with lower and upper limits, which are related to the buckling and rupture mechanisms of the bubble. Further discussion is made regarding the effects resulting from the change of the surface tension coefficient on bubble dynamics. The dynamic responses of Optison and Sonozoid microbubbles, measured experimentally based on light scattering technology (adapted from previously published work), are simulated using both classic three-layer models (e.g. Church s model) and simplified model. The results show that our simplified model works as well as the Church s model.