Investigation of mitochondrial DNA genetic diversity and phylogeny of goats worldwide
Investigation of mitochondrial DNA genetic diversity and phylogeny of goats worldwide作者机构:College of Animal Science and TechnologySouthwest UniversityChongqing 400715P.R.China Chongqing Agriculture and Rural Affairs Committee of TongnanChongqing 402660P.R.China Dazhou Animal Husbandry Technology Extension StationDazhou 635299P.R.China Institute of Animal SciencesChinese Academy of Agricultural SciencesBeijing 100193P.R.China
出 版 物:《Journal of Integrative Agriculture》 (农业科学学报(英文版))
年 卷 期:2022年第21卷第6期
页 面:1830-1837页
核心收录:
学科分类:0905[农学-畜牧学] 09[农学] 090501[农学-动物遗传育种与繁殖]
基 金:funded by the Chongqing Natural Science Foundation, China (cstc2021jcyj-msxm X0013) the National Natural Science Foundation of China (31172195)
主 题:mitochondrial DNA genetic diversity population structure population expansion phylogeny
摘 要:Genetic diversity,population structure,and population expansion of goats worldwide(4165 individuals from 196 breeds)were analyzed using published mitochondrial DNA(mtDNA)D_loop hypervariable region *** showed that 2409 haplotypes and 301 polymorphic sites were present within the 401-bp length D_loop region,the nucleotide diversity(Pi)was 0.03471,and the haplotype diversity(Hd)was *** analysis revealed that 98.92%of haplotypes were divided into six obvious clusters,consistent with the classification of the known mitochondrial haplogroups of *** A accounted for the largest proportion(86%).Interestingly,two unknown divisions(Unknown I and Unknown II)were discovered from goats in Southwest China,suggesting that Southwest China has unique maternal *** of molecular variance(AMOVA)and the average number of pairwise differences between populations(PiXY)indicated that geographical variation was small but *** tests(Tajima’s D and Fu’s FS tests)and mismatch distribution showed that haplogroups B,C,and G had expansion *** addition,the phylogenetic relationship between domestic and wild goats suggested that Capra aegagrus is the most likely wild ancestor and may have participated in the domestication of ancestral populations of A,B,C,and F haplogroups.A meta-analysis on the mtDNA sequences of goats from international databases was conducted to analyze goats’genetic diversity,population structure,and matrilineal system evolution *** results may help further understand the domestication history and gene flow of goats worldwide.