Biomedical applications of the powder-based 3D printed titanium alloys:A review

作     者：Amy X.Y.Guo Liangjie Cheng Shuai Zhan Shouyang Zhang Wei Xiong Zihan Wang Gang Wang Shan Cecilia Cao Amy X.Y.Guo;Liangjie Cheng;Shuai Zhan;Shouyang Zhang;Wei Xiong;Zihan Wang;Gang Wang;Shan Cecilia Cao

作者机构：Materials Genome InstituteShanghai UniversityShanghai 200444China 

出 版 物：《Journal of Materials Science & Technology》 (材料科学技术（英文版）)

年 卷 期：2022年第125卷第30期

页      面：252-264页

核心收录：

学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0802[工学-机械工程] 080201[工学-机械制造及其自动化] 

基　　金：financial support provided by the National Key Research and Development Program of China(Grant No.2017YFB0701600) Key Program of Science and Technology of Yunnan Province(Grant No.202002AB080001-2) 

主　　题：The powder-based 3D printing technology Ti-based alloys Biomedical applications Artificial intelligence 

摘      要：3D printing technology is a new type of precision forming technology and the core technology of the third industrial *** powder-based 3D printing technology of titanium and its alloys have received great attention in biomedical applications since its advantages of custom manufacturing,costsaving,time-saving,and resource-saving *** particular,the personalized customization of 3D printing can meet specific needs and achieve precise control of micro-organization and structural *** purpose of this review is to present the most advanced multi-material 3D printing methods for titanium-based *** first reviewed the bone tissue engineering,the application of titanium alloy as bone substitutes and the development of manufacturing technology,which emphasized the advantages of 3D printing technology over traditional manufacturing *** is more,the optimization design of the hierarchical structure was analyzed to achieve the best mechanical properties,and the biocompatibility and osseointegration ability of the porous titanium alloy after implantation in living bodies was ***,we emphasized the development of digital tools such as artificial intelligence,which provides new ideas for the rational selection of processing *** 3D printing titanium-based alloys will meet the huge market demand in the biomedical field,but there are still many challenges,such as the trade-off between high strength and low modulus,optimization of process parameters and structural *** believe that the combination of mechanical models,machine learning,and metallurgical knowledge may shape the future of metal printing.