Evaluation of proximal tubule functions in children with COVID‑19:a prospective analytical study

作     者：Fatma Devrim Elif Böncüoğlu Elif Kıymet ŞahikaŞahinkaya Ela Cem Mine Düzgöl Aybüke Akaslan Kara KamileÖtiken Arıkan AslıKantar Ebru Yılmaz Nida Dinçel Nuri Bayram İlker Devrim Fatma Devrim;Elif B?ncüo?lu;Elif Kiymet;?ahika ?ahinkaya;Ela Cem;Mine Düzg?l;Aybüke Akaslan Kara;Kamile ?tiken Arikan;Ash Kantar;Ebru Yilmaz;Nida Din?el;Nuri Bayram;ilker Devrim

作者机构：Department of Pediatric NephrologyUniversity of Health Sciences Dr.Behçet Uz Child Disease and Pediatric Surgery Training and Research HospitalİzmirTurkey Department of Pediatric Infectious DiseasesUniversity of Health Sciences Dr.Behçet Uz Child Disease and Pediatric Surgery Training and Research HospitalİzmirTurkey 

出 版 物：《World Journal of Pediatrics》 (世界儿科杂志（英文版）)

年 卷 期：2022年第18卷第9期

页      面：607-612页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Coronavirus disease 2019(COVID-19) Proteinuria Proximal tubular dysfunction Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Tubular reabsorption of phosphate 

摘      要：Background There are limited numbers of studies focusing on renal efects of coronavirus disease 2019(COVID-19)infection and proximal tubular dysfunction in children with COVID-19 *** purpose of this study was to evaluate the functions of the proximal tubule in hospitalized children with confrmed acute *** The children who were hospitalized for confrmed COVID-19 were included in this prospective descriptive *** presence of at least two of the following four abnormalities was used to diagnose proximal tubule injury:abnormal tubular reabsorption of phosphate,normoglycemic glycosuria,hyperuricosuria,and *** A total of 115 patients were included in the *** a third of the individuals had elevated blood creatinine levels or *** addition,abnormal renal tubular phosphate loss measured by renal tubular phosphate loss was found in 10(8.7%)patients,as was hyperuricosuria in 28.6%.As a result,total proximal tubular dysfunction was found in 24(20.9%)*** One in every fve children with acute COVID-19 infections had proximal tubular dysfunction,according to our ***,the rate of proximal tubular dysfunction was lower than in adults,it should be *** recovery of proximal tubular function in children with COVID-19 should be followed.