Leptomeningeal metastasis from central nervous system tumors: A study of classification and stage in the spinal canal of 58 patients

作     者：ZHANG MingShan OU YunWei ZHANG HongWei ZHANG JunPing XIA Lei QU YanMing WANG HaoRan ZHAN QiMin SONG YongMei YU ChunJiang 

作者机构：Department ofNeurosurgery Beijing Sanbo Brain Hospital Capital Medical University Beijing 100093 China Department ofNeuro-oncology Beijing Sanbo Brain Hospital Capital Medical University Beijing 100093 China State Key Laboratory of Molecular Oncology Cancer Institute Cancer Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100021 China 

出 版 物：《Chinese Science Bulletin》 (中国科学通报)

年 卷 期：2012年第57卷第22期

页      面：2914-2919页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：恶性肿瘤细胞 蛛网膜下腔 中枢神经系统 患者 分期研究 分类 脑 磁共振成像 

摘      要：Leptomeningeal metastasis (LM) is caused by the spread of malignant tumor cells into the subarachnoid ***,classification and staging of LM in the spinal canal is rare in the *** authors reviewed the records of 58 Chinese patients with LM for clinical features,neuroimaging,and ***-enhanced magnetic resonance imaging (MRI) of brain and spinal cord were performed in all *** of intracranial tumors was performed in all patients and diagnoses were confirmed by *** study group consisted of 58 patients,with 29 cases presenting with intraspinal *** the 58,8 patients underwent intraspinal tumor removal,8 received radiotherapy alone,9 received chemotherapy alone,and 34 patients received combined *** classified LM into 3 types:type L or leptomeninges LM,is subdivided into 2 subtypes (subtype LI and LII (a,b)),type N or nerve root LM is subdivided into 2 subtypes (subtype NI and NII (a,b)),and type M or mixed-type *** also divided LM into stages of I-IV according to the symptoms and the volume of the tumor based on spinal axial *** LI LM often occurs in patients with intracranial and intraspinal tumors found *** who receive surgery for intracranial tumors may present with type N *** is suitable for patients with NI LM and LIIb LM in stages III-IV,presenting with severe spinal *** prognosis is better for type N LM than type L LM.