Bioceramic-based scaffolds with antibacterial function for bone tissue engineering:A review
作者机构：State Key Laboratory of High Performance Ceramics and Superfine MicrostructureShanghai Institute of CeramicsChinese Academy of SciencesShanghai200050PR China Center of Materials Science and Optoelectronics EngineeringUniversity of Chinese Academy of SciencesBeijing100049PR China School of Materials and ChemistryUniversity of Shanghai for Science and TechnologyShanghai200093PR China
出 版 物：《Bioactive Materials》 (生物活性材料（英文）)
年 卷 期：2022年第7卷第12期
页 面：383-398页
核心收录：
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学]
基 金：the National Natural Science Foundation of China(No.51872185,52072246,32130062) Science and Technology Commission of Shanghai Municipality(No.20442420300) China Postdoctoral Science Foundation(No.2021M703332)
主 题：Bioceramic-based scaffolds Implant-associated infection Antibacterial activity Bone repair Bone tissue engineering
摘 要：Bone defects caused by trauma,tumor,congenital abnormality and osteoarthritis,*** been substantially impacted the lives and health of *** bone implants,like bioceramic-based scaffolds,provide significant benefits over biological counterparts and are critical for bone repair and ***,it is highly probable that bacterial infections occur in the surgical procedures or on bioceramic-based ***,it is of great significance to obtain bioceramic-based scaffolds with integrative antibacterial and osteogenic functions for treating bone implant-associated infection and promoting bone *** fight against infection problems,bioceramic-based scaffolds with various antibacterial strategies are developed for bone repair and regeneration and also have made great *** review summarizes recent progresses in bioceramic-based scaffolds with antibacterial function,which include drug-induced,ion-mediated,physical-activated and their combined antibacterial strategies according to specific antibacterial ***,the challenges and opportunities of antibacterial bioceramic-based scaffolds are discussed.
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