Anti-fatigue activity of Brassica rapa *** and correlation among biochemical changes in forced swimming mice
作者机构：State Key Laboratory of Food Science and TechnologySchool of Food Science and TechnologyJiangnan UniversityWuxi214122China International Joint Laboratory on Food SafetyJiangnan UniversityWuxi214122China People's Liberation Army Air ForcePLABeijing100142China
出 版 物：《Food Bioscience》 (食品生物科学（英文）)
年 卷 期：2022年第47卷第3期
页 面：670-678页
核心收录：
学科分类：1002[医学-临床医学] 100216[医学-运动医学] 10[医学]
主 题：Brassica rapa L. UHPLC-MS Anti-fatigue Behavioral experiment Energy metabolism
摘 要：Brassica rapa *** an edible and medical plant in China used for treating various diseases,especially in the Tibet *** this study,the chemical constituents of Brassica rapa ***(BE)was clarified by UHPLC-MS and anti-fatigue ability of BE was assessed through the behavior test and weight-loaded forced swimming test in *** we determined several biochemical parameters related to fatigue to explore possible *** indicate that BE could significantly enhance exercise performance in mice,and there was a significant improvement in both grip-strength and the time on ***,BE showed significant anti-fatigue effects by decreasing the blood lactic acid(BLA),blood urea nitrogen(BUN),and creatine kinase(CK)levels and increasing the lactate dehydrogenase(LDH)and malondialdehyde(MDA)*** in superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)were observed and reactive oxygen species(ROS)levels was *** and muscle glycogen levels and adenosine triphosphate(ATP)levels were also significantly *** correlation analysis indicates that fatigue-related indexes including metabolites and energy-related indexes were significantly correlated with antioxidant *** conclusion,BE possesses remarkable anti-fatigue activity,thereby shows great potential for improving exercise performance and alleviating physical fatigue and can be considered as a functional food supplement for further development.
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