Comparison of Avian Osteopetrosis Images Obtained by Electron Microscopy and Radiology

作     者：YUEXue-min CHENBai-xi WUYi-fang 

作者机构：VeterinaryDiagnosticResearchLaboratoryofSouthChinaAgriculturalUniversityGunangzhou510642P.R.China ElectronMicroscopyLaboratoryofSunYat-senUniversityofMedicalSciencesGuangzhou510089P.R.China 

出 版 物：《Agricultural Sciences in China》 (中国农业科学（英文版）)

年 卷 期：2003年第2卷第8期

页      面：930-936页

学科分类：090603[农学-临床兽医学] 09[农学] 0906[农学-兽医学] 

基　　金：supported by the National Natural Science Foundation of China(39770570) 

主　　题：Chicken Avian osteopetrosis Radiology Electron microscopy 

摘      要：After being examined by radiology, 30 chickens with experimental and natural osteopetrosis(OP)were selected for electron microscopy to make clear the relationship between radiological lesions and ul-trastructural appearances. Fourteen cases were positive(+), 4 cases were moderate(+ +), 6 cases were strong(+ + +), 3 cases were suspicious(±), and 3 cases were negative(-)control. Electron micrographs of tibiae from 30 cases were examined. Bones of the 3 controls were ultrastructurally normal. Virions were observed in suspicious cases and positive cases(+, + +, + + +). In size, morphology and ultrastructure, they resembled avian type C oncoviruses. The observation provides pathogenic evidence for OP radiological diagnosis. The OP suspicious cases and positive cases(+, + + , + + +)had ultrastructural changes characterized by osteocyte necrosis, enlarged bone lacunae and vascular lesions etc. The correlation between radiology and e-lectron microscopy provided ultrastructural evidence for OP radiological diagnosis.