Absence of sperm meiotic segregation error of chromosomes 1, 9,12,13,16,18, 21, X and Y in a case of 100% necrozoospermia

作     者：Ashutosh Halder Vandana Chaddha Savita Agarwal Ashish Fauzdar ASHUTOSH HAIDER;VANDANA CHADDHA;SAVITA AGARWAL;ASHISH FAUZDAR DEPARTMENT OF MEDICAL GENETICS;SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES;LUCKNOW;INDIA

作者机构：Department of Medical Genetics Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow IndiaDepartment of Medical Genetics Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow IndiaDepartment of Medical Genetics Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow IndiaDepartment of Medical Genetics Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow India 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2003年第5卷第2期

页      面：163-166页

核心收录：

学科分类：0502[文学-外国语言文学] 050201[文学-英语语言文学] 05[文学] 

主　　题：oligospermia necrozoospermia fluorescent in situ hybridization 

摘      要：Varying degrees of necrozoospermia are common findings in cases of male sub-fertility; however, it is rare to find persistent and 100 % necrozoospermia. A case of persistent 100 % necrozoospermia is presented in this paper, where aneuploidy analysis was carried out on sperm. No known associations like thyrotoxicosis, genital infection, spinal injury and diabetes were found. Sperm fluorescent in situ hybridization (FISH) was carried out to evaluate sperm aneuploidy for chromosome 1, 9, 12, 13, 16, 18, 21, X and Y and did not show any excess of aneuploidy over controls. To the best of our knowledge, this is the first attempt on meiotic segregation analysis on 100 % necrozoospermic patient.