Insult of gastroesophageal reflux on airway： clinical significance of pharyngeal nozzle

作     者：Zhonggao Wang Zhiwei Hu Jimin Wu Feng Ji Hongtao Wang Yungang Lai Xiang Gao Yachan Ning Chengchao Zhang Zhitong Li Weitao Liang Jianjun Liu 

作者机构：Center for GER the Second Artillery General Hospital of PLA Beijing 100088 China Xuanwu Hospital Capital Medical University Beijing 100053 China Center for GER the First Ajfiliated Hospital of Zhengzhou University Zhengzhou 450052 China Center for GER the Fourth Affiliated Hospital of Zhengzhou University Zhengzhou 450044 China 

出 版 物：《Frontiers of Medicine》 (医学前沿（英文版）)

年 卷 期：2015年第9卷第1期

页      面：117-122页

核心收录：

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 1002[医学-临床医学] 081704[工学-应用化学] 07[理学] 080704[工学-流体机械及工程] 08[工学] 0817[工学-化学工程与技术] 0807[工学-动力工程及工程热物理] 

主　　题：gastroesophageal reflux airway pharyngeal nozzle micro-aspiration asthma 

摘      要：At the very time of global paying the highest attention to the worst insults of smoking as well as haze on the airway, everybody knows both are exogenous and noticeable. However, people mostly, including many medical personnel, do not know how badly the gastroesophageal reflux （GER） insults on our own airway. Symptoms of GER are commonly seen as heartburn and regurgitation, which can be mostly tolerated. However, when the up going gastric content reversely passes the esophagus and then the distal pharynx, where it appears a beak like stricture, serving as a nozzle, so as to produce numerous micro-particles and reach the oro-nasal cavity and also the airway causing allergic rhinitis and asthmatic attacks, even pulmonary parenchyma lesions. It will reduce life quality or even jeopardize life. The point that the endogenous insult appears in the respiratory system, but originates from the digestive tract is not well known and often undiagnosed and not correctly treated. The GER induced airway challenge is a treatable and preventive entity, as soon as a diagnosis is made, a good relief could be expected by means of life style adjustment, medicine, or fixation of the patulous cardia through radiofrequency or fundoplication. The author Dr. Zhonggao Wang had suffered it for long and symptoms disappeared for 8 years after anti-reflux surgery. Here is a presentation of Dr. Zhonggao Wang and his team＇s work and would call attention to the public so as to recognize this relatively unknown entity -- a treatable condition occurring from human itself, but not from outside surroundings as smoking or haze does.