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Anti-ulcer activity of Ficus religiosa leaf ethanolic extract

Anti-ulcer activity of Ficus religiosa leaf ethanolic extract

作     者:Marslin Gregory B. Divya Revina Ann Mary M. M. Hipolith Viji V. K. Kalaichelvan V. Palanivel 

作者机构:Department of pharmacology Annamalai UniversityChidambaram India Centre for the Research and Technology of Agro-Environment and Biological Sciences (CITAB) Department of Biology University of MinhoPortugal Padmavathi College of Pharmacy and Research Institute Periyanahalli DharmapuriTamilnadu India Department of Nursing Science A.J College of Nursing ChennaiTamilnadu India Department of Phytochemistry Natural Remedies Research lab BangaloreKarnataka India 

出 版 物:《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志(英文版))

年 卷 期:2013年第3卷第7期

页      面:554-556页

学科分类:1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主  题:Ficus religiosa Flavonoids Ethanolic extract Ulcer area Ranitidne 

摘      要:Objective:To evaluate the anti-ulcer activity and acute toxicity ofFicus religiosa(F. religiosa)leaf ethanolic extract in animal ***:Anti-ulcer activity ofF. religiosaethanolicextract(250 and 500 mg/kg body weight) was studied on stress induced ulcer animal *** was used as standard. The anti-ulcer activity ofF. religiosawas evaluated with thehelp of ulcer area and histopatholgical examination. Preliminary phyto-chemical screeningand acute toxicity studies ofF. religiosaalso carried ***:Results showed that theextract treatments prevented ulcer area and gastric secretion in a dose-dependent *** of 2000 mg/kg extract did not show any acute toxicity in albino mice. Preliminaryphytochemical analysis identified the presence of flavonoids in the ethanolic extract ofF. ***:The extract is non-toxic even at relatively high concentrations. The anti-ulceractivity is probably due to the presence of flavanoids.

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