Current highlights on solid pseudopapillary neoplasm of the pancreas
作者机构：Department of Surgery Pietro ValdoniSapienza University of RomeUmberto I HospitalRome 00161Italy Minimally Invasive Surgery UnitTor Vergata HospitalTor Vergata University of RomeRome 00133Italy
出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)
年 卷 期：2022年第14卷第1期
页 面：300-303页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Pseudopapillary neoplasm Pancreatic tumor Pancreaticoduodenectomy Distal pancreatectomy Pancreas Surgery
摘 要：Solid pseudopapillary neoplasm of the pancreas is a low-grade malignant tumor that predominantly affects young women in their third and fourth *** and risk factors are *** symptoms are aspecific and most commonly due to mass *** is made by computed tomography scan or magnetic resonance imaging and histological characterization is obtained by endoscopic ultrasound-guided fine needle ***,these lesions are composed by both solid and pseudopapillary structures with necrotic and hemorrhagic ***,the biological behavior is aggressive with tumor recurrence and distant ***,curative R0 surgical resection is the best option able to provide long term survival even in advanced *** disease is the main predictor of poor *** and radiotherapy regimens are not well ***,they could be effective in reducing tumor size as neoadjuvant treatment or disease control in palliative *** complete surgical resection provides a cure rate of95%,considering young age of the patients and morbidity associated to pancreatic surgery,further studies are needed to better investigate risk factors and responsiveness to hormones in order to allow early diagnosis and follow up strategies that could avoid unnecessary surgery in less aggressive disease.
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