Nanotheranostics:A powerful next-generation solution to tackle hepatocellular carcinoma

作     者：Rusdina Bte Ladju Zulvikar Syambani Ulhaq Gita Vita Soraya 

作者机构：Department of Anatomic PathologyFaculty of MedicineHasanuddin UniversityMakassar 90245Indonesia Department of BiochemistryFaculty of Medicine and Health SciencesMaulana Malik Ibrahim Islamic State UniversityMalang 65151Indonesia National Research and Innovation AgencyCentral Jakarta 10340Indonesia Department of BiochemistryFaculty of MedicineHasanuddin UniversityMakassar 90245Indonesia Department of NeurologyFaculty of MedicineHasanuddin UniversityMakassar 90245Indonesia 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2022年第28卷第2期

页      面：176-187页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Hepatocellular carcinoma Hepatic cancer Nanotheranostic Nanoplatform Personalized medicine Future therapy 

摘      要：Hepatocellular carcinoma(HCC)is an epidemic burden and remains highly prevalent *** significant mortality rates of HCC are largely due to the tendency of late diagnosis and the multifaceted,complex nature of ***,current therapeutic modalities such as liver resection and transplantation are only effective for resolving early-stage ***,alt-ernative approaches are required to improve detection and enhance the efficacy of current treatment *** platforms,which utilize biocompatible nanoparticles to perform both diagnostics and targeted delivery,has been considered a potential approach for cancer management in the past few *** of nanomaterials and biomedical engineering techniques has led to rapid expansion of the nanotheranostics field,allowing for more sensitive and specific diagnosis,real-time monitoring of drug delivery,and enhanced treatment efficacies across various *** focus of this review is on the applications of nanotheranostics for *** review first explores the current epidemiology and the commonly encountered obstacles in HCC diagnosis and *** then presents the current technological and functional advancements in nanotheranostic technology for cancer in general,and then specifically explores the use of nanotheranostic modalities as a promising option to address the key challenges present in HCC management.