Cryogel scaffolds: soft and easy to use tools for neural tissue culture

作     者：Ben Newland Katherine R.Long Ben Newland;Katherine R.Long

作者机构：School of Pharmacy and Pharmaceutical SciencesCardiff UniversityCardiffUK Centre for Developmental NeurobiologyInstitute of PsychiatryPsychology and NeuroscienceKing’s College LondonMRC Centre for Neurodevelopmental DisordersKing’s College LondonLondonUK 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2022年第17卷第9期

页      面：1981-1983页

核心收录：

学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：MRC [MR/S025065/1  MR/N026063/1] Funding Source: UKRI 

主　　题：culture neural transient 

摘      要：The mammalian central nervous system(CNS)is highly complex,with a vast array of processes and interactions occurring in a dynamic and often transient *** these processes are combined to regulate our behavior remains poorly *** has in turn led to a lack of understanding of how these processes have gone awry in the many disorders of the nervous *** order to address this,researchers need a controlled way to manipulate the nervous system in in vitro and ex vivo cultures,in both a specific area and for a specific period of time to start to pick apart these *** date,this has been technically challenging,especially when modeling focal injury to the CNS or when working with human brain tissue.