The Current State and Perspectives of Systems Biology

作     者：Tielui Shi 

作者机构：Bioinformation Center Shanghai Institutes for Biological Sciences. CAS. Shanghai 200032 Bioinformation Center. Shanghai University Shanghai 200444 Shanghai Center for Bioinformation Technology Shanghai 200235 

出 版 物：《Science Foundation in China》 (中国科学基金（英文版）)

年 卷 期：2006年第14卷第1期

页      面：48-53页

学科分类：08[工学] 09[农学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：中国科学院资助项目 

主　　题：系统生物学 生物系统建模 高吞吐量 基因调节网络 蛋白质 

摘      要：Emerging as a new field in biology recently, Systems Biology provides a branch new way to study the biological activities in organisms. In order to decode the complexity of life systematically, systems biology integrates the -omics and uses the high throughput methods from transcriptomics, protomics and metabonomics to detect the dynamic activities in cell; and then, it incorporates bioinfor-matics methods to integrate and analyze those data, and simulate the biological processes based on the model built from those integrated data. In this paper, the current state, the research field and the methods for the Systems Biology are introduced briefly, and then, several ideas about future development in this field are also proposed.