Adhesive anastomosis for organ transplantation

作     者：Kang Liu Hang Yang Gaobo Huang Aihua Shi Qiang Lu Shanpei Wang Wei Qiao Haohua Wang Mengyun Ke Hongfan Ding Tao Li Yanchao Zhang Jiawei Yu Bingyi Ren Rongfeng Wang Kailing Wang Hui Feng Zhigang Suo Jingda Tang Yi Lv 

作者机构：National Local Joint Engineering Research Center for Precision Surgery and Regenerative MedicineDepartment of Hepatobiliary SurgeryFirst Affiliated Hospital of Xi’an Jiaotong UniversityXi’an710061Shaanxi ProvinceChina State Key Lab for Strength and Vibration of Mechanical StructuresInternational Center for Applied MechanicsDepartment of Engineering MechanicsXi’an Jiaotong UniversityXi’an710049China John A.Paulson School of Engineering and Applied ScienceKavli Institute for Bionano Science and TechnologyHarvard UniversityCambridgeMA02138USA Hepatobiliary Surgery DepartmentShaanxi Provincial People’s HospitalXi’an710068Shaanxi ProvinceChina 

出 版 物：《Bioactive Materials》 (生物活性材料（英文）)

年 卷 期：2022年第7卷第7期

页      面：260-268页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：This work was supported by grants from the Key R&D Project of Shaanxi Province(No.2020GXLH-Z-001) the National Key R&D Project of China(No.2018YFC0115300 and No.2018YFC0115305) the National Natural Science Foundation of China(No.81727802,12172272,11702208,11820101001) China Postdoctoral Science Foundation(No.BX201700192,2018M643620) 

主　　题：Magnet Hydrogel Adhesive Anastomosis Liver transplantation 

摘      要：The recent development of tough tissue adhesives has stimulated intense interests among material scientists and medical ***,these adhesives have seldom been tested in clinically demanding *** we demonstrate adhesive anastomosis in organ *** is commonly conducted by dense sutures and takes a long time,during which all the vessels are *** occlusion may damage organs and even cause *** formulate a tough,biocompatible,bioabsorbable adhesive that can sustain tissue tension and pressurized *** expose the endothelial surface of vessels onto a gasket,press two endothelial surfaces to the adhesive using a pair of magnetic rings,and reopen the bloodstream *** time for adhesive anastomosis is shortened compared to the time for sutured *** have achieved adhesive anastomosis of a great vein in transplanting the liver of a *** the surgery,the adhesive is absorbed,the vein heals,and the pig lives for over one month.