Pathway Matters: Prefrontal Control of Negative Emotions via Distinct Downstream Regions

作     者：Junqiang Zheng Na Liu Han Xu Junqiang Zheng;Na Liu;Han Xu

作者机构：Department of Neurobiology and Department of Neurology of the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310058China NHC and CAMS Key Laboratory of Medical NeurobiologyMOE Frontier Science Center for Brain Research and Brain-Machine IntegrationSchool of Brain Science and Brain MedicineZhejiang UniversityHangzhou 310058China 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2022年第38卷第2期

页      面：226-228页

核心收录：

学科分类：0710[理学-生物学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 071006[理学-神经生物学] 

基　　金：supported by grants from the National Natural Science Foundation of China(3212501&32071005) the Fundamental Research Funds for the Central Universities(2019QNA5001) 

主　　题：inactivation precise Mount 

摘      要：The infralimbic cortex(IL)is a major subregion of the medial prefrontal cortex(mPFC)that is essential for many advanced brain functions including *** studies have unraveled a critical role of the IL in the processing of negative emotions such as fear and ***,these studies also generate controversial data regarding the precise functions of the IL in the regulation of either fear or *** one hand,pharmacological inactivation of the IL attenuates anxiety-like behaviors and consistently,pharmacological activation of the IL produces anxiety-like behaviors[1].