Performance of HEART and TIMI scores in predicting major adverse cardiovascular events(MACEs)of chest pain patients in the emergency department:A prospective observational study

作     者：Sonal Kaushal Ginoya Samira N.Parikh Sonal Kaushal Ginoya;Samira N.Parikh

作者机构：Department of Emergency MedicineGCS Medical CollegeHospital and Research CentreAhmedabadIndia 

出 版 物：《Journal of Acute Disease》 (急性病杂志（英文版）)

年 卷 期：2021年第10卷第5期

页      面：190-194页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Chest pain Emergency Major adverse cardiovascular events MACEs HEART TIMI 

摘      要：Objective:To compare the value of HEART and TIMI scores in predicting major adverse cardiovascular events(MACEs)of patients with chest pain in the emergency department at a tertiary care hospital in Ahmedabad,a city in western ***:A prospective study was conducted on chest pain patients from January to December *** adult patients with non-traumatic chest pain presenting to the emergency department were included,and their HEART and TIMI scores were *** patients were followed up within 4 weeks for monitoring any major adverse cardiac events or *** receiver-operating characteristics(ROC)curve was used to determine the value of HEART and TIMI scores in predicting ***,the specificity,sensitivity,positive predictive value(PPV),and negative predictive value(NPV)of the two scores were assessed and ***:A total of 350 patients were evaluated[mean age(55.03±16.6)years,56.6%of males].HEART score had the highest predictive value of MACEs with an area under the curve(AUC)of 0.98,followed by the TIMI score with an AUC of *** score had the highest specificity of 98.0%(95%CI:96.4%-99.6%),the sensitivity of 75.0%(95%CI:70.7%-79.3%),and PPV of 97.0%(95%CI:94.1%-99.9%)and NPV of 82.5%(95%CI:74.6%-90.4%)for low-risk *** score had a specificity of 95.0%(95%CI:92.4%-97.6%),sensitivity of 75.0%(95%CI:69.4%-80.6%),PPV of 92.3%(95%CI:88.1%-96.5%)and NPV of 82.3%(95%CI:73.8%-90.8%)for low-risk ***:HEART score is an easier and more practical triage instrument to identify chest pain patients with low-risk for MACEs compared to TIMI *** with high HEART scores have a higher risk of MACEs and require early therapeutic intervention and aggressive management.