Liver disease and COVID-19:The link with oxidative stress,antioxidants and nutrition
作者机构:Group for Nutritional Biochemistry and DietologyCentre of Research Excellence in Nutrition and MetabolismNational Institute for Medical ResearchUniversity of BelgradeBelgrade 11129Serbia
出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))
年 卷 期:2021年第27卷第34期
页 面:5682-5699页
核心收录:
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金:the Ministry of Education Science and Technological Development of the Republic of Serbia No.451-03-9/2021-14/200015
主 题:SARS-CoV-2 COVID-19 Liver injury Antioxidants Nutrients Treatment
摘 要:Varying degrees of liver injuries have been reported in patients infected with the severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2).In general,oxidative stress is actively involved in initiation and progression of liver *** liver metabolizes various compounds that produce free *** the oxidative/antioxidative balance is important in coronavirus disease 2019(COVID-19)*** vitamins,essential trace elements and food compounds,such as polyphenols,appear to be promising agents,with effects in oxidative *** of these nutrients suppresses immune function and increases susceptibility to *** micronutrient intake is necessary to support anti-inflammatory and antioxidative effects but for immune function may be higher than current recommended dietary *** supplements(β-carotene,vitamin A,vitamin C,vitamin E,and selenium)could have a potential role in patients with liver *** evidence suggests that supplementing the diet with a combination of micronutrients may help to optimize immune function and reduce the risk of *** trials based on the associations of diet and SARS-CoV-2 infection are ***,it is not possible to definitively determine the dose,route of administration and best timing to intervene with antioxidants in COVID-19 patients because clinical trials are still *** then,hopefully,this review will enable clinicians to understand the impact of micronutrient dietary intake and liver status assessment in COVID-19 patients.