Effects of Environmental Cadmium on Cadmium Accumulation, Oxidative Response, and Microelements Regulation in the Liver and Kidney of Hexagrammos otakii

作     者：HU Fawen SUN Ming LI Li GAO Fengxiang JIAN Yuxia WANG Xue WANG Xiaolong GUO Wen HU Fawen;SUN Ming;LI Li;GAO Fengxiang;JIAN Yuxia;WANG Xue;WANG Xiaolong;GUO Wen

作者机构：Marine Biology Institute of Shandong ProvinceHealthy Mariculture Engineering Research Center of Shandong ProvinceQingdao 266104China 

出 版 物：《Journal of Ocean University of China》 (中国海洋大学学报（英文版）)

年 卷 期：2022年第21卷第2期

页      面：479-485页

核心收录：

学科分类：07[理学] 09[农学] 0903[农学-农业资源与环境] 0713[理学-生态学] 

基　　金：supported by the Key Technology Re-search and Development Program of Shandong Province(Nos.2019GHY112071 and 2019GHY112062) the Major Agricultural Application Technology Innovation Pro-jects in Shandong Province(No.SD2019YY007) 

主　　题：accumulation oxidative response ionoregulatory toxicity waterborne cadmium Hexagrammos otakii 

摘      要：The effects of cadmium(Cd)on metal accumulation,microelements contents,and antioxidant responses in Hexagram-mos otakii were *** fish were exposed to 0.2,2.5,or 10μg L−1 Cd for 12 or 24 ***,the concentration of Cd and mi-croelements(Ca,Fe,Zn,and Se)were determined in the liver and ***,the activities of antioxidant enzymes including superoxide dismutase(SOD),catalase(CAT),and glutathione-S-transferase(GST),and the content of malondialdehyde(MDA)in the liver and kidney were also measured.A continuous accumulation of Cd was observed throughout the experimental *** accumulation was higher in liver than that in the kidney,while Ca and Fe contents were lower in liver than those in the *** exposure resulted in a decrease of Ca and Fe concentrations in the kidney,while there was no effect on the *** and Se remained unaffected with exposure to *** exposure induced severe oxidative stress in ***,as indicated by significant induction of the activities of SOD,CAT,and GST,and a simultaneous increase of MDA *** data show that antioxidant enzymes and mi-croelements contents can be used as potential biomarkers to monitor environmental health in fish.