Female sex in experimental traumatic brain injury research:forging a path forward
Female sex in experimental traumatic brain injury research:forging a path forward作者机构:Department of Child HealthUniversity of Arizona College of Medicine-Phoenix BARROW Neurological Institute at Phoenix Children’s HospitalPhoenixAZUSA Phoenix VA Health Care SystemPhoenixAZUSA Arizona State UniversityTempeAZUSA
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2022年第17卷第3期
页 面:550-552页
核心收录:
学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
基 金:supported by the National Institutes of Health (R01NS100793) Phoenix Children's Hospital Mission Support
摘 要:Traumatic brain injury(TBI) is a leading cause of death and disability worldwide,with estimates indicating that -50% of the world s population will acquire a head injury at some point in their lifetime(Maas et al.,2017).Mild TBIs account for -80% of all reported cases,with up to 43% of all TBI patients reporting symptoms beyond 2 weeks *** of 2016,only 7% of preclinical TBI experiments included both male and female sexes,and fewer studies analyzed the data using sex as a biological variable(Spani et al.,2018).