Nanocellulose,a versatile platform:From the delivery of active molecules to tissue engineering applications
作者机构：Department of Biosystems EngineeringInstitute of Forest ScienceKangwon National UniversityChuncheon24341Republic of Korea Interdisciplinary Program in Smart AgricultureKangwon National UniversityChuncheon24341Republic of Korea Deptarment of Engineering DesignIndian Institute of TechnologyMadras600036India
出 版 物：《Bioactive Materials》 (生物活性材料（英文）)
年 卷 期：2022年第7卷第3期
页 面：566-589页
核心收录：
学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学]
基 金：This research was supported by the Basic Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(NRF-2018R1A6A1A03025582) and the National Research Foundation of Korea(NRF-2019R1D1A3A03103828)
主 题：Nanocellulose Chemical functionalization Drug delivery Protein delivery Plasmid delivery Tissue engineering
摘 要：Nanocellulose,a biopolymer,has received wide attention from researchers owing to its superior physicochemical properties,such as high mechanical strength,low density,biodegradability,and *** can be extracted from wide range of sources,including plants,bacteria,and *** on the extraction process and dimensions(diameter and length),they are categorized into three main types:cellulose nanocrystals(CNCs),cellulose nanofibrils(CNFs),and bacterial nanocellulose(BNC).CNCs are a highly crystalline and needle-like structure,whereas CNFs have both amorphous and crystalline regions in their *** is the purest form of *** nanocellulose properties can be tuned by chemical functionalization,which increases its applicability in biomedical *** review highlights the fabrication of different surface-modified nanocellulose to deliver active molecules,such as drugs,proteins,and ***-mediated delivery of active molecules is profoundly affected by its topographical structure and the interaction between the loaded molecules and *** applications of nanocellulose and its composites in tissue engineering have been ***,the review is concluded with further opportunities and challenges in nanocellulose-mediated delivery of active molecules.
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