Can omalizumab be used effectively to treat severe conjunctivitis in children with asthma?A case example and review of the literature
作者机构：Department of PaediatricsRoyal Belfast Hospital for Sick ChildrenBelfast BT126BAUnited Kingdom Department of Paediatric Education and SimulationRoyal Belfast Hospital for Sick ChildrenBelfast BT126BAUnited Kingdom Department of Child HealthQueens University BelfastBelfast BT126BJUnited Kingdom Centre of Medical EducationQueens University BelfastSchool of MedicineBelfast BT97BLUnited Kingdom Department of Paediatric RespiratoryRoyal Belfast Hospital for Sick ChildrenBelfast BT126BAUnited Kingdom
出 版 物：《World Journal of Clinical Pediatrics》 (世界临床儿科杂志)
年 卷 期：2021年第10卷第4期
页 面：48-52页
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100212[医学-眼科学] 100202[医学-儿科学] 10[医学]
主 题：Omalizumab Conjunctivitis Allergy Asthma Pediatrics Atopy
摘 要：A 14-year-old girl with poorly controlled asthma attended the difficult-to-treat asthma clinic for *** she has eosinophilia and significantly raised immunoglobulin E levels,she is not currently a candidate for omalizumab(Xolair).She also suffers from chronic urticaria,eosinophilic eosophagitis and severe *** wonder if omalizumab would be effective in treating her multiple atopic conditions,in particular her troublesome *** was searched using the following search terms:(Omalizumab)or(Xolair)and(conjunctivitis).Searches were conducted in November *** were selected for full text review if the study population identified asthma as a ***-paediatric studies and those that were not written in English were *** use of omalizumab has the potential to be effective in the treatment of conjunctivitis associated with asthma and other atopic ***,research is needed to address the question,in the form of multicenter,double-blind randomized control trials.
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