Current and New Drugs for COVID-19 Treatment and Its Effects on the Liver

作     者：Sandeep Satsangi Nitin Gupta Parul Kodan Sandeep Satsangi;Nitin Gupta;Parul Kodan

作者机构：Department of Apollo comprehensive Liver CareApollo HospitalBangaloreKarnatakaIndia Department of Infectious DiseasesKasturba Medical CollegeManipal Academy of Higher EducationManipalKarnatakaIndia Department of MedicineAll India Institute of Medical SciencesNew DelhiIndia 

出 版 物：《Journal of Clinical and Translational Hepatology》 (临床与转化肝病杂志（英文版）)

年 卷 期：2021年第9卷第3期

页      面：436-446页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：COVID-19 Drugs Liver Drug-induced liver injury 

摘      要：Corona virus disease(COVID)-19 is caused by the novel severe acute respiratory syndrome coronavirus-2(commonly referred to as SARS-CoV-2).In March 2020,the World Health Organization declared the COVID-19 outbreak a *** the target organ for the virus is primarily the lungs,with the recent understanding of the pathobiology of this disease and the immune dysregulation associated with it,it is now clear that COVID-19 affects multiple organ *** drugs and therapies have been tried or repurposed to combat the wrath posed by this *** October 22,2020,the USA Food and Drug Administration approved remdesivir for use in adults and pediatric patients(12 years of age and older).Several of the drugs being tried against COVID-19 have hepatotoxicity as their potential side *** review aims to provide the latest insights on various drugs being used in the treatment of COVID-19 and their effects on the liver.