Development of a PVA Hydrogel for Bioprosthetic Heart Valve Stent and Other Medical Applications

作     者：Z.F.Zhang 

作者机构：Department of Chemical and Biochemical EngineeringLondon Ontario University of Western Ontario The John Robarts Research InstituteLondon Ontario Department of Chemical and Medical BiophysicsLondonOntario Department of Chemical and CardiologyLondonOntario University of Western Ontario The John Robarts Research InstituteLondonOntario University of Western Ontario The John Robarts Research InstituteLondon Ontario The University Campus London Health Sciences Center London Ontario Canada 

出 版 物：《材料科学与工程学报》 (Journal of Materials Science and Engineering)

年 卷 期：2000年第20卷第Z2期

页      面：988-992页

核心收录：

学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

主　　题：PVA hydrogel Bioprosthetic heart valve stent design and fabrication tensile test fatigue medical applications 

摘      要：Polyvinyl alcohol (PVA) hydrogel (15%w/w) was processed by freezing and thawing from one through six thermal cycles to obtain wide range of mechanical properties. The materials were tested under uniaxial tension and results show that matching mechanical properties to that of porcine aortic root can be achieved. A fatigue machine for elastomer materials and tissues was built and fatigue test on PVA sample was carried out. The test results show that the PVA has good fatigue property. The stent prototype was designed and successfully made by mold casting method. Some potential medical applications are discussed.