Printed microelectrode arrays on soft materials:from PDMS to hydrogels

作     者：Nouran Adly Sabrina Weidlich Silke Seyock Fabian Brings Alexey Yakushenko Andreas Offenhausser Bernhard Wolfrum 

作者机构：Institute of Bioelectronics(ICS-8)and JARA-Fundamentals of Future Information TechnologyForschungszentrum JulichJulich 52425Germany Neuroelectronics-Munich School of BioengineeringDepartment of Electrical and Computer EngineeringTechnical University of MunichBoltzmannstrase 11D-85749 GarchingGermany 

出 版 物：《npj Flexible Electronics》 (npj-柔性电子（英文）)

年 卷 期：2018年第2卷第1期

页      面：111-119页

核心收录：

学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：Norbert Wolters and Jan Schnitker for help with the amplifier development and acknowledge funding by the Bernstein Center Munich(grant number 01GQ1004A,BMBF) We greatly appreciate the funding from the BCCN(grant number 01GQ1004A,BMBF) 

主　　题：PDMS printing arrays 

摘      要：Microelectrode arrays(MEAs)provide promising opportunities to study electrical signals in neuronal and cardiac cell networks,restore sensory function,or treat disorders of the nervous ***,most of the currently investigated devices rely on silicon or polymer materials,which neither physically mimic nor mechanically match the structure of living tissue,causing inflammatory response or loss of ***,we present a new method for developing soft MEAs as bioelectronic *** functional structures are directly deposited on PDMS-,agarose-,and gelatin-based substrates using ink-jet printing as a patterning *** demonstrate the versatility of this approach by printing high-resolution carbon MEAs on PDMS and *** soft MEAs are used for in vitro extracellular recording of action potentials from cardiomyocyte-like HL-1 *** results represent an important step toward the design of next-generation bioelectronic interfaces in a rapid prototyping approach.