In situ growth of polydopamine on surface of covalent organic frameworks under the catalysis of acid phosphatase for dopamine detection

作     者：Fei Qu Ziwei Guo Dafeng Jiang Xian-En Zhao Fei Qu;Ziwei Guo;Dafeng Jiang;Xian-En Zhao

作者机构：The Key Laboratory of Life-Organic AnalysisQufu Normal UniversityQufu 273165China The Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural MedicineQufu Normal UniversityQufu 273165China Department of Physical and Chemical TestingShandong Center for Disease Control and PreventionJi'nan 250014China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2021年第32卷第11期

页      面：3368-3371页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 1010[医学-医学技术（可授医学、理学学位）] 070302[理学-分析化学] 0703[理学-化学] 10[医学] 

基　　金：supported by the Natural Science Foundation of Shandong Province,China(No.ZR2019QB010) National Natural Science Foundation of China(Nos.21705095,21775088) the Scientific Research Foundation of Qufu Normal University(No.BS D20130117) 

主　　题：Fluorescence Enzyme Polydopamine Dopamine Acid phosphatase 

摘      要：Dopamine(DA)is easy to be oxidized and polymerizes to form polydopamine(pDA)in alkaline conditions,while the synthesis is usually time-consuming(48 h).Herein,the polymerization of DA is completed with 4 h under the catalysis of acid phosphatase(ACP).The high efficiency makes the detection of DA feasibility based on the self-polymerization of *** this assay,pDA is grown in situ on the surface of covalent organic frameworks(COFs),and then the fluorescence of COFs is quenched *** linear range of DA is achieved from 0.5-50μmol/L with a detection limit of 0.16μmol/*** detection of DA is not interfered with uric acid,ascorbic acid,and some phenolic compounds,because these substances cannot polymerize in the presence of ***,benefiting from the good sensitivity and selectivity,DA has been successfully determined by this strategy in human urine samples with satisfactory recoveries.