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Papular acantholytic dyskeratosis of the anogenital area with novel ATP2C1 gene mutations

Papular acantholytic dyskeratosis of the anogenital area with novel ATP2C1 gene mutations

作     者:Xue-Min Xiao Yi-Qun Jiang Wei Tian Cheng-Rang Li Xiao Xue-Min;Jiang Yi-Qun;Tian Wei;Li Cheng-Rang

作者机构:Department of DermatologyThe Union HospitalFujian Medical UniversityFuzhouFujian 350001China Institute of DermatologyJiangsu Key Laboratory of Molecular Biology for Skin Diseases and Sexually Transmitted InfectionsChinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China 

出 版 物:《Chinese Medical Journal》 (中华医学杂志(英文版))

年 卷 期:2021年第134卷第12期

页      面:1508-1510页

核心收录:

学科分类:1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学] 

基  金:supported by grants from the National Natural Science Foundation of China(Nos.81602785 and 81472872) the Natural Science Foundation of Fujian,China(No.2017J05128) Fujian Provincial Health Technology Project(No.2019-ZQN-47) the Opening Foundation of Research Platform of Fujian University of Traditional Chinese Medicine(No.X2018018-Platform) 

主  题:diseases kerato sis 

摘      要:To the Editor:Focal acantholytic dyskeratosis(FAD)is used to describe a group of diseases with diverse clinical manifestations but characteristic histological *** 1984,the first case of“papular acantholytic dyskeratosis(PAD)of the vulvocrural areawas reported in a 23-year-old female with pathological manifestations of FAD and the researchers believed that it might be a new independent disease.[1]Recently,the relationship between PAD and Hailey-Hailey disease(HHD)as well as Darier disease(DD)is receiving increasing attention from *** performed gene mutation screening in two patients with sporadic PAD and explored the nature of PAD.

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